Health agencies scramble to prepare for new mpox strain – The Mercury News

Ariel Cohen | CQ-Roll Call (TNS)

WASHINGTON — State and federal health agencies are gearing up to respond to a new strain of mpox — the virus formerly known as monkeypox — if the new strain spreads to the United States.

But this time, they are doing so with fewer resources.

Both an mpox public health emergency declaration and federal pandemic preparedness law were still in effect in 2022, the last time the U.S. faced a widespread mpox outbreak. That gave the federal government and state health departments more resources and flexibility than it has now to deal with an outbreak.

Last month, the World Health Organization declared a public health emergency of international concern, the highest alarm under international health law, over the new mpox strain. The strain, known as clade 1b, has been rapidly circulating in central Africa and has been detected in Sweden and Thailand.

The new strain differs from the 2022 world outbreak of the clade IIb mpox strain, which U.S. officials treated with two doses of the JYNNEOS mpox vaccine. Much like the COVID-19 vaccines, the mpox shot JYNNEOS prevents severe infection, hospitalization and death from mpox, but doesn’t fully prevent transmission, according to the Centers for Disease Control and Prevention.

Clade 1b is endemic in the Democratic Republic of Congo, and the strain is more widespread than any other outbreak. Clade 1b usually causes a higher percentage of people with mpox to get severely sick and die, compared to clade IIb, according to the CDC.

While clade 1b has not yet been detected in the U.S., state and federal health officials are gearing up for what could be a potentially worse outbreak than in 2022 by leaning on the lessons it learned two years ago.

“It’s a different ballgame than in 2022, in some ways that are better and in some ways that are TBD,” Jen Kates, senior vice president and director of global health and HIV policy at KFF, said. She noted that public health jurisdictions today are already armed with mpox vaccines and treatments, unlike in 2022.

Budgeting for vaccines

The State Department says it’s been preparing for clade 1b’s emergence in the U.S. since December 2023 through increased monitoring of wastewater and other surveillance systems. But access to public health surveillance systems has waned since the COVID-19 public health emergency ended.

And the 2022 mpox public health emergency allowed the federal government to more easily free up resources to produce and distribute vaccines to high-risk groups at no cost.

The federal government ended the emergency declaration in 2023, but JYNNEOS vaccine maker Bavarian Nordic privatized the vaccine earlier this year. Now states must order it on the commercial market. State health officials said the budget is more of a concern now that vaccines are privatized.

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