For the second time in less than 40 days, the 49ers are facing the Seattle Seahawks on Sunday.
In their recent meeting on Oct. 12, the 49ers raced out to a 23-3 lead in the third quarter, then allowed that margin to dip to just five points before sealing a 36-23 win.
This time, the 49ers will have the NFL’s reigning Offensive Player of the Year, Christian McCaffrey, who returned to action last week in a win over the Buccaneers after missing the season’s first two months with Achilles tendinitis.
McCaffrey will contribute to a run game that has been dominant in the 49ers’ six-game win streak over Seattle.
The Seahawks won’t have starting center Connor Williams for the matchup after he retired this week, citing personal reasons.
San Francisco has several stars listed as questionable on the injury list entering Sunday afternoon: Left tackle Trent Williams is dealing with ankle and wrist injuries, while Bosa has a hip injury and George Kittle has a hamstring issue. Starting guard Aaron Banks (thigh) is questionable, too, while punter Mitch Wishnowsky was placed on injured reserve this week as the 49ers signed Pat O’Donnell to punt.
Meanwhile, cornerback Charvarius Ward will miss a second consecutive game as he mourns his daughter’s death.
Seattle receiver DK Metcalf is expected back from a two-game absence due to a knee injury.
Follow along below for game updates…