New option for treating prostate cancer
Prostate cancer is the second most common cancer in men worldwide. Despite medical advances in recent years, this type of tumour is still responsible for one in eight male cancer …
Prostate Cancer; Men
Innovative model provides valuable insights into prostate cancer spread
A new preclinical model using CRISPR, an advanced technology that allows scientists to cut and edit genes, has given Weill Cornell Medicine researchers and their colleagues a deeper insight into …
A common culprit drives prostate cancer progression
By tracking the changes in prostate cancer cells over time, researchers at the Johns Hopkins Kimmel Cancer Center have found that activation of the MYC gene — a well-known cancer-causing …
Inflammatory cells in tumor microenvironment promote the transformation of prostate cancer cells into treatment-resistant cells
There is a challenge related to prostate and many other cancers that cancer cells form resistance to treatments as the disease progresses. However, these resistance mechanisms are not yet fully …
Chromatin openness sheds new light on prostate cancer plasticity
Treatment resistance caused by cancer cell plasticity constitutes a major challenge in the treatment of prostate cancer. Published in Nucleic Acids Research, a recent study from the University of Eastern …
Protein discovery could help solve prostate cancer drug resistance
Researchers have identified a receptor protein known as CHRM1 as a key player in prostate cancer cells’ resistance to docetaxel, a commonly used chemotherapy drug to treat advanced cancer that …
Blood test distinguishes neuroendocrine subtype of advanced prostate cancer
Like a criminal entering a witness protection program, cancer cells can shed their past and take on a new identity. Detecting such an identity-switch is particularly challenging when metastatic castration-resistant …